VB.NET Listbox Database-like File Link

I am working on a project, and I want to create a Listbox that will look at a file to determine what to display on the Listbox, and I want to have a button on a WinForm to launch a program, corresponding to what the user has selected.
I feel like doing it through a database-like file will be easier to code, but I have no clue where to start. Could someone give me some advice? Thanks!

(PS: I would post this on Stack Overflow, if I could post questions. My account was banned for asking questions because they didn’t get any attention on them.)