Connection timeouts

Has anyone else been experiencing connectivity issues with GitHub over the last few days.
Here we have remotely hosted servers authenticating with a mix of legacy (username + password over HTTPS) as well as SSH-key authentication and when DNS resolves to, it directly refuses to connect on either protocol. Even the browser is affected.
We get a “connection refused” error for both, but only when DNS resolution resolves to the above IP.
If I change the hosts file to a different IP-address, it works fine.

If you want to know whether the problem was on GH side or due to some other network elements, you might consult the GitHub Status reports: