A Python based stock analysis environment

My question - How should I proceed to successfully get my project implemented?

Background -
I want to implement a python based environment to create, analyze and chart various stock trading parameters. I see there are already quite a few good open source packages that I one can use to as a starting point - Pandas, TA-Lib, Matplotlib, etc.

Using these, I need to build a few more layers on top to integrate data from a few sources and create my own custom studies and visualize them on the chart as well as compare them against various other studies and securities.

Some examples of what people have done with these are noted below as examples.

Any advise would be appreciated.

Thank you.
Best regards,